Connecticut has awarded $9.8 million in stem cell research funds to 19 researchers.
The awards were made by the state’s Stem Cell Research Advisory Committee at its recent grant review meeting week.
In January, 88 stem cell funding applications were accepted for review, officials said Monday.
The committee says it culled them in accordance with National Institutes of Health guidelines and provided to the Advisory Committee its recommendations with respect to the scientific merits of each application.
The following are the panel’s awards:
Evaluating the endogenous potential for brain repair in primary progressive multiple sclerosis using induced pluripotent stem cells
University of Connecticut Health Center, Farmington
Stephen Crocker, Principal Investigator
$200,000
RNA targets of the stemness factor LIN-28
Yale University, New Haven
Frank Slack, Principal Investigator
$200,000
Modeling Hypertrophic Cardiomyopathy (HCM) Using Human Induced Pluripotent Stem Cells
Yale University, New Haven
Yongming Ren, Principal Investigator
$200,000
Direct differentiation of human iPSCs facilitated by mechanical forces
Yale University, New Haven
Jing Zhou, Principal Investigator
$200,000
Embryonic and pluripotent stem cell- produced factors as novel therapeutic candidates for improved aged muscle function and regenerative responses in humans
University of Connecticut Health Center, Farmington
Morgan Carlson, Principal Investigator
$200,000
Mechanical factors influencing the differentiation of human embryonic stem cells
Yale University, New Haven
Eric Dufresne, Principal Investigator
$200,000
Genome-wide shRNA screen identifies novel regulatory pathways in human ES cells
Yale University, New Haven
Zheng Wang, Principal Investigator
$200,000
Stem Cells for cell therapy of hypoparathyroidism
Yale University, New Haven
Julie Ann Sosa, Principal Investigator
$200,000
Transcriptional Control of Pluripotency in Human ES Cells
Yale University, New Haven
Natalia Ivanova, Principal Investigator
$750,000
Inducing immune tolerance to hESCs and their derivatives by the hESC derived thymic epithelial cells
University of Connecticut, Storrs
Laijun Lai, Principal Investigator
$750,000
Generation of functional keratinocytes from hESCs
Yale University, New Haven
Valerie Horsley, Principal Investigator
$750,000
Remyelination potential of human ES cell derived OPCs transplanted into the demyelinated nonhuman primate spinal cord
Yale University, New Haven
Jeffrey Kocsis, Principal Investigator
$750,000
Molecular Regeneration of the Neuronal development by MeCP2
Yale University, New Haven
In-Hyun Park, Principal Investigator
$750,000
A study of the chromatin structure of maternal and paternal 15q alleles to discover therapies for Prader-Willi syndrome
University of Connecticut Health Center, Farmington
Stormy Chamberlain, Principal Investigator
$450,000
Regulation of muscle stem cell programming
University of Connecticut, Storrs
David Goldhamer, Principal Investigator
$450,000
Human tissue-engineered blood vessels using induced pluripotent stem cells
Yale University, New Haven
Yibing Qyang, Principal Investigator
$750,000
UCONN-Wesleyan Stem Cell Core Powered with More Cutting Edge Technologies
University of Connecticut Health Center, Farmington/Wesleyan University, Middletown
Ren-He Xu/Laura Grabel, Principal Investigator
$500,000
Continued service and technology development at the Yale stem cell center cores
Yale University, New Haven
Haifan Lin, Principal Investigator
$500,000
Are dopaminergic neurons derived from human embryonic stem cells or from fibroblasts the best candidates for treatment for Parkinson’s disease as studied in the best primate model
Yale University, New Haven
D. Eugene Redmond, Principal Investigator
$1,800,000
